Home > Main Course > Seafood > Baked Tilapia and Vegetable Casserole

Baked Tilapia and Vegetable Casserole

This Baked Tilapia & Veggie Casserole is so Juicy and Flaky. Easy, excellent dish! @natashaskitchen

This post may contain affiliate links. Read my disclosure policy.

You have to try this fish casserole! I knew it was a winner with the first bite. The recipe was given to us by my Mama-in-law and her friend shared it with her. When a recipe gets shared over and over, you know it’s good. Seriously, this is MOUTH-WATERING! It also tastes healthy and light. The tilapia is juicy and flaky without a hint of fishiness.

The sweet veggies complement it beautifully. If you aren’t a fan of tilapia, you can easily substitute your favorite fish and get the same delicious results. I want more! We ate it up real quick! This dish is perfect for company. It is easy to make, smells and tastes delicious and your guests and family will love it.

This Baked Tilapia & Veggie Casserole is so Juicy and Flaky. Easy, excellent dish! @natashaskitchen

Tilapia Ingredients:

2 lbs (about 6-10 count) Tilapia fillets, thawed
Olive Oil to saute
1 Tbsp ketchup (several readers had great results with Sriracha instead of ketchup)
1 Tbsp mayo

Marinade Ingredients:

2 large eggs
1 cup buttermilk
2 Tbsp soy sauce
1/2 tsp Salt and 1/8 tsp Pepper

Vegetable Ingredients:

2 medium bell peppers (red, orange, or yellow)
2 medium/large carrots, julienned or grated
1 medium onion

Tilapia and Vegetable Casserole

How to Make Tilapia and Vegetable Casserole:

1. Whisk together marinade ingredients. Combine with tilapia in a large ziploc bag or bowl and marinate in the fridge at least 1 1/2 hours.

Tilapia and Vegetable Casserole-4

2. Slice onions into thin half circles, slice bell pepper into thin strips and julienne or grate carrots. In a large skillet over medium/high, heat 2-3 Tbsp oil and saute onions for 3 minutes or until softened. Add sliced bell peppers and carrots and saute another 4-5 min or until softened. Remove from pan and set veggies aside.

Tilapia and Vegetable Casserole-5

3. Once fish is done marinating, drain and discard marinade. In the same empty skillet over medium/high, add 2-3 Tbsp oil and saute fish lightly on the skillet just until golden on the outside (about 2 min per side) – it’s ok if it’s not cooked through completely at this point. Also, it probably would have been easier to turn the fish on a non-stick skillet :-O.

Tilapia and Vegetable Casserole-6

4. Layer the casserole dish with 1/2 of the vegetables on the bottom. Place fish over the vegetables. Stir together 1 Tbsp ketchup and 1 Tbsp mayo and brush this mixture evenly over the top of the fish. Cover fish with remaining veggies. Sprinkle the top with salt and pepper to taste then cover tightly with foil or lid and bake at 375˚F for 15 min.

Tilapia and Vegetable Casserole-7

This Baked Tilapia & Veggie Casserole is so Juicy and Flaky. Easy, excellent dish! @natashaskitchen

This Baked Tilapia & Veggie Casserole is so Juicy and Flaky. Easy, excellent dish! @natashaskitchen

Tilapia and Vegetable Casserole Recipe

4.94 from 63 votes
Author: Natasha of NatashasKitchen.com
You have to try this fish casserole! It tastes healthy and light. The fish is juicy and flaky without a hint of fishiness and the sweet veggies complement the savory fish beautifully.
Prep Time: 1 hour 30 minutes
Cook Time: 30 minutes
Total Time: 2 hours

Ingredients 

Servings: 6 Servings

Tilapia Ingredients:

  • 2 lbs about 6-10 count Tilapia fillets, thawed
  • Olive Oil to saute
  • 1 Tbsp ketchup, several readers had great results with sriracha instead of ketchup
  • 1 Tbsp mayo

Marinade Ingredients:

  • 2 eggs
  • 1 cup buttermilk
  • 2 Tbsp soy sauce
  • 1/2 tsp Salt and 1/8 tsp Pepper

Vegetable Ingredients:

  • 2 medium bell peppers, (red, orange or yellow)
  • 2 medium/large carrots, julienned or grated
  • 1 medium onion

Instructions

  • Whisk together marinade ingredients. Combine with tilapia in a large ziploc bag or bowl and marinate in the fridge 1 1/2 hours.
  • Slice onions into thin half circles, slice bell pepper into thin strips and julienne or grate carrots. In a large skillet over medium/high, heat 2-3 Tbsp oil and saute onions for 3 min or until softened. Add sliced bell peppers and carrots and saute another 4-5 min or until softened. Remove from pan and set aside.
  • Once fish is done marinating, drain and discard marinade. In the same empty skillet over medium/high, add 2-3 Tbsp oil and saute fish lightly on the skillet just until golden on the outside (about 2 min per side) - it's ok if it's not fully cooked through at this point.
  • Layer the casserole dish with 1/2 of the vegetables on the bottom, then Place fish over the vegetables. Stir together 1 Tbsp ketchup and 1 Tbsp mayo and brush this mixture evenly over the top of the fish. Cover fish with remaining veggies. Sprinkle the top with salt and pepper to taste then cover tightly with foil or lid and bake at 375˚F for 15 min.
Course: Main Course
Cuisine: American
Keyword: Tilapia and Vegetable Casserole
Skill Level: Easy/Medium
Cost to Make: $$
Natasha's Kitchen Cookbook

Final Final Picmonkey Hashtag banner

This Baked Tilapia & Veggie Casserole is so Juicy and Flaky. Easy, excellent dish! @natashaskitchen

♥ FAVORITE THINGS ♥
Shown in this post: (nope, no one paid us to write this; just stuff we love):
* It’s so handy to have multiple sizes of liquid measuring cups.
* This is my favorite baking casserole dish. I love that it has a lid!
* We search high & low for a perfect julienne slicer. This Swissmar is it!
* If using a slicer or mandolin, you have to try these safety gloves!

Natasha Kravchuk

Welcome to my kitchen! I am Natasha, the creator behind Natasha's Kitchen (established in 2009), and I share family-friendly, authentic recipes. I am a New York Times Best-Selling cookbook author and a trusted video personality in the culinary world. My husband, Vadim, and I run this blog together, ensuring every recipe we share is thoroughly tested and approved. Our mission is to provide you with delicious, reliable recipes you can count on. Thanks for stopping by! I am so happy you are here.

Read more posts by Natasha

4.94 from 63 votes (22 ratings without comment)

Leave a Comment

Recipe Rating




Comments

  • Mila
    April 11, 2024

    Quick Question: If I want to prepare this a day in advance for a party the next day (it will go in an oven right before the party) would I change anything? Do I still bake it like the last step tells me to and then reheat the next day?

    Reply

    • NatashasKitchen.com
      April 11, 2024

      Hi Mila! For food safety reasons, it is not recommend to partially cook meat and then refrigerate it so I do not recommend assembling ahead.

      Reply

  • Anna
    November 8, 2022

    I followed the recipe and it’s just OK. There really wasn’t anything special about the final product. I felt like it was missing something. I added tomato sauce (in addition to the ketchup in the recipe) and some spice and it made it better. But overall I was disappointed.

    Reply

As Featured On

Never Go "Hangry" Again!

Get weekly updates on new recipes, exclusive giveaways plus behind the scenes photos.